(Senior) Lab Technician – Translational Research (m/f/d)

(Senior) Lab Technician - Translational Research (m/f/d)

Date posted: May, 2022
Location Vienna, Austria

About HOOKIPA:

HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies that mobilize and amplify targeted T cells to address unmet needs in cancer.

This leveraging its proprietary, versatile platform to engineer a broad pipeline of differentiated arenaviral therapeutics. These novel immunotherapies induce robust antigen-specific killer T cells to a broad range of self and non-self antigens, including viral antigens, tumor-associated antigens and neoantigens. HOOKIPA's platform technology uses replicating viral vectors based on the target cancer, with the potential to induce killer T cell response levels previously not achieved by other immunotherapy approaches.

HOOKIPA's pipeline includes wholly-owned investigational arenaviral immunotherapeutics targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed projects. In addition, the company aims to develop functional cures of HBV and HIV in collaboration with Gilead.

Position Summary:

We seek an experienced, highly motivated (Senior) Lab Technician with expertise in immunological assays and cell culture to join our dynamic Translational Research Team in the Preclinical & Translational Research Department. Working closely with scientists and peers you will be establishing, optimizing, and performing immunological assays including working with clinical specimen for mechanistic characterization of novel therapies. Further, you will support developing innovative therapeutic approaches using preclinical models and moving lead candidates into clinical development. In this position, you will be using a wide range of in vitro techniques.

Main Responsibilities:

• Perform immunoassays (e.g., multicolor flow cytometry, ELISA, multiplex cytokine profiling)
• Perform in vitro assays with human PBMCs and cell lines (e.g., transfection, ELISpot, cytotoxicity, proliferation, live cell imaging)
• Develop, optimize, and establish translational in vitro and ex vivo assays
• Execute, analyze, and present experiments in department meetings
• Cell culture of cell lines and primary cells (e.g., moDCs)
• Human tissue preparation and processing (e.g., PBMCs)
• Work with infectious materials under BSL-2 conditions
• Documentation of experiments according to internal guidelines
• Maintenance of laboratory equipment and material stocks
• Ability to work on weekends and statutory holidays if necessary

Qualifications & Skills:

• MTA, BTA, Dipl. Ing. (FH), B.Sc., M.Sc. or equivalent in relevant field (e.g., Biology, Immunology, Microbiology, Biotechnology)
• 1+ year of relevant hands-on lab experience (e.g., cell culture, immunoassays, BSL-2)
• Understanding of the concepts of immunology and immuno-oncology
• Experience with cell culture, flow cytometry, immunological assays and human PBMCs is a must
• Experience with molecular biology techniques (e.g., qPCR, transduction) is a plus
• Eager to acquire new knowledge, to learn, develop and optimize novel techniques
• Independent, efficient, proactive, well organized, solution- and detail-oriented, hands-on mentality
• Motivated, flexible team player with the ability to handle multiple tasks in parallel and deliver high quality results under tight timelines
• MS Office and data analysis skills (GraphPad Prism, FlowJo)
• Strong interest in working in a creative environment and in participating in all aspects of preclinical development
• Excellent communication skills in English; German is a plus

What we offer:

• Strong international team with dedicated and passionate scientists and technicians
• State of the art infrastructure
• Excellent working atmosphere
• Opportunities for personal development
• Working in a multinational and multicultural environment
• Employee benefits such as health screening, public transportation card, Sodexo pass

We are required by Austrian law to post a minimum salary. The minimum monthly gross salary from EUR 2.754,- (Lab Technician) to EUR 3.233,- (Senior Lab Technician) based on fulltime (40 hours per week). Depending on experience and qualification salary can be negotiated. In addition, we offer a performance-related bonus payment and participation in our stock option compensation program.

Starting date: as soon as possible

Contact:

If you are interested in this challenging position, please send your CV including a cover letter summarizing your qualification and experiences to: talent@hookipapharma.com

For more information on HOOKIPA please visit www.hookipapharma.com